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targets pathways that are commonly activated in cancer cells•
systemic delivery to distant tumor sites following localized or systemic administration•
systemic delivery optimized by naturally occurring stealth form of the product generated by viral replication in tumor cells•
multiple systemic efficacy mechanisms by inducing immune response and vascular shutdown•
large capacity to deliver multiple therapeutic payloads•
imaging tags•
efficient spread with broad spectrum of tumor killing•
long history of safety in humans
